QB Issue Resolution:

If you are running on a Mac, and you are updating QuickBooks, the most likely cause is that the update didn’t complete. Fortunately you can download the program again from here:

http://support.quickbooks.intuit.com/Support/ProductUpdates.aspx?lid=UpdateDownloads%20(SUB%20HDR)

Resolution for Issue 'I can’t open my program.Program was working on my Mac until an upgrade.' available: Yes (Solved).
Source: Intuit Community forum.

I can’t open my program.Program was working on my Mac until an upgrade.: this issue or error code is a known issue in Quickbooks Online (QBO) and/or Quickbooks. Support for this issue is available either by self-service or paid support options. Experts are available to resolve your Quickbooks issue to ensure minimal downtime and continue running your business. First try to resolve the issue yourself by looking for a resolution described below. If it is a complex issue or you are unable to solve the issue, you may contact us by clicking here or by using other support options.

Support for program
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Error Recovery for program [Canada]
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Additional Support Options: