QB Issue Resolution:
We’ll have to check the browser’s zoom and computer display settings. I’ve got you the article with the steps depending on the browser and operating system you’re using: Unable to see the entire page in QuickBooks Online. Once done, create the invoice again.
Resolution for Issue 'Invoice is missing save buttons' available: Yes (Solved).
Source: Intuit Community forum.
Invoice is missing save buttons: this issue or error code is a known issue in Quickbooks Online (QBO) and/or Quickbooks. Support for this issue is available either by self-service or paid support options. Experts are available to resolve your Quickbooks issue to ensure minimal downtime and continue running your business. First try to resolve the issue yourself by looking for a resolution described below. If it is a complex issue or you are unable to solve the issue, you may contact us by clicking here or by using other support options.Support for Invoice
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Error Recovery for Invoice [Canada]
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