QB Issue Resolution:
Most of the printer preferences are stored in the QuickBooks Prefs. You can throw those out and start again.
To do so:
0. Quit QuickBooks
1. In the finder, hold down the option key, and select Go->Library.
2. A finder window will open to the ~/Library directory. Double click on the Preferences folder.
3. Within the Preferences folder, drag com.intuit.QuickBooks2014.plist to the trash.
4. Restart QuickBooks
If that doesn’t fix it, when printing next time hold down the option key when you click on the print button. That clears some other (internal) preferences.
Resolution for Issue 'My print settings have somehow been altered and I have to make changes with each transaction. How can I set defaults?' available: Yes (Solved).
Source: Intuit Community forum.
My print settings have somehow been altered and I have to make changes with each transaction. How can I set defaults?: this issue or error code is a known issue in Quickbooks Online (QBO) and/or Quickbooks. Support for this issue is available either by self-service or paid support options. Experts are available to resolve your Quickbooks issue to ensure minimal downtime and continue running your business. First try to resolve the issue yourself by looking for a resolution described below. If it is a complex issue or you are unable to solve the issue, you may contact us by clicking here or by using other support options.Support for Quickbooks
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